Victory for FC would see them climb back to the top of the Super League table, and they would stay there if Wigan fail to beat Leeds on Friday evening.
Victory over the Robins would also end Rovers’ hopes of making the Super Eights, and condemn them to the Qualifiers.
“It’s a special game, one we all look forward to and a game everyone will be up for,” Radford told his club’s official website.
“We’ve got a chance to knock them (Hull KR) into the bottom four. If that doesn’t whet your lips as a Black and White, not much else does.”