Widnes are seeking their first victory against Hull at the KC Stadium, having lost on all six previous visits.
Brown has scored five tries so far this season, and he needs three more for a career total of 100.
Squad: Arundel, Colbon, Crooks, Ellis, Hadley, Heremaia, Horne, Houghton, Kent, Paleaaesina, Rankin, Shaul, Talanoa, Thompson, Tuson, Watts, Westerman, Whiting, Yeaman.
Last match: Lost 19-16 away at Castleford
Squad: Ah Van, Brown, Clarke, Craven, Dean, Flynn, Galea, Gerrard, Gilmore, Hanbury, Isa, Johnson, Joseph, Kavanagh, Leuluai, Phelps, Marsh, Tickle, White.
Last match: Lost 38-4 away at Leeds
Super League summary
Hull FC won 9
Widnes won 4
Hull FC highest score: 72-10 (H, 2013) (widest margin: 70-4, H, 2004)
Widnes highest score: 46-10 (H, 2003) (also widest margin)