It promises to be a lot closer than the last time the two nations met, when Steve McCormack’s men racked up a 104-0 victory in Padova back in 2009.
Scotland will once again look to draw upon the passionate support of the Workington crowd, having attracted the biggest attendance to Derwent Park since 1994 in Tuesday night’s win.
Prop Anthony Laffranchi said: “We are improving every week and the community within the players is improving.
“We are getting to know each other a bit more and obviously playing together on a weekly basis helps.
The winner of this game is likely to be in pole position for a place in the quarter-finals, where the likely opponent would be New Zealand.
Scotland squad:: Danny Addy (Bradford), Danny Brough (Huddersfield), Brett Carter (Workington), Luke Douglas (Gold Coast), Dale Ferguson (Huddersfield), Ben Fisher (London), Ian Henderson (Catalan), Ben Hellewell (Featherstone), Alex Hurst (London), Ben Kavanagh (Widnes), Kane Linnett (North Queensland), Brett Phillips (Workington), Matt Russell (Gold Coast), David Scott (Featherstone), Mitchell Stringer (Sheffield), Alex Szostak (Sheffield), Adam Walker (Hull KR), Peter Wallace (Brisbane), Oliver Wilkes (Wakefield)
Italy squad: Christophe Calegari (Lezignan), Chris Centrone (North Sydney), Cameron Ciraldo (Penrith), Ben Falcone (Souths Logan), Ryan Ghietti (Northern Pride), Aidan Guerra (Sydney), Anthony Laffranchi (St Helens), Joshua Mantellato (Newcastle), Tim Maccan (Tweed Heads), Anthony Minichiello (Sydney), Mark Minichiello (Gold Coast), Raymond Nasso (Avignon), Dean Parata (Parramatta), Joel Riethmuller (North Queensland), Brendan Santi (Wests), Kade Snowden (Newcastle), James Tedesco (Wests), Ryan Tramonte (Windsor), Paul Vaughan (Canberra)