The Bulls were without several first-team players and paid the price in the second half when Jason Demetrious grabbed two tries, along with touchdowns from Adam Watene, Matt Blaymire, Peter Fox and Ben Jeffries.
Bradford grabbed consolation tries in the second half through youngster Paul Mennell and new signing Glen Morrison, but that was not enough to prevent a wide margin of defeat.
Meanwhile, Harlequins faced a tough battle at the hands of newly promoted Hull Kingston Rovers, but managed to secure a narrow 24-18 win at Craven Park.
And Warrington Wolves ran in five tries as they beat Salford City Reds 24-12 at The Willows.
Danny Halliwell had opened the scoring for the Reds before Henry Fa’afili responded for the Wolves, who settled matters in the second half with tries from Martin Gleeson, David Gower, Rob Parker, and another from Fa’afili.