Catalans trio Kenny Edwards, David Mead and Mickael Simon will all miss Friday’s trip to Hull FC.
Simon, 32, is the latest to be confirmed missing due to concussion protocol rules.
Mead was stretchered off during the 50-14 loss to St Helens last weekend, while Edwards also went off injured.
The Dragons have remained in England since the Saints game.
After the Hull trip, Catalans’ next game starts their Challenge Cup defence at home to League One side Doncaster.