Saints have already sold over 8,000 tickets for this intriguing clash, and Knowsley Road is guaranteed to be packed to the rafters with supporters of both sides.
St Helens have already lifted the Powergen Challenge Cup and, having been the best side over 28 rounds of engage Super League football, the League Leaders’ Shield; they will now be looking to complete the treble.
"This is the best team I've coached, easily," said Saints boss Daniel Anderson, adding, "I don't say that lightly.”
"It's a fantastic team. There are some gifted hard old heads, great leadership and brilliant young footballers" he continued.
The Airlie Birds are no doubt confident, and coach Peter Sharp is undaunted at the prospect of being labelled the under-dogs.
"I've no problems with going into the game as underdogs," he said. "All season we have flown under the radar, both as a team and as individuals.
"Our players don't get the profile the Saints players do and, as a team, we have gone a little unnoticed considering we finished second.
However, Sharp also pointed out that the earlier win at Knowsley road will count for nothing tonight.
"But they also have weaknesses like any side and we are capable of beating them."
This game is likely to be a titanic tussle between two sides dreaming of Grand Final glory, with the possibility of meeting again on the Old Trafford stage in a fortnight’s time.