Regan Grace will return for St Helens on Friday, while Leeds’ Tui Lolohea is on international duty with Tonga.
St Helens coach Justin Holbrook has made two changes to his side that beat Huddersfield last week. Grace and Matty Lees replace Adam Swift and Joseph Paulo.
Richard Agar has made one change to his Leeds outfit that lost to Wigan last time out. Matt Parcell comes in for Lolohea.
Jack Walker could also return to action for the Rhinos.
The televised Super League match takes place at the Totally Wicked Stadium on Friday, 7:45pm kick-off.
St Helens’ 19-man squad: Jonny Lomax, Tommy Makinson, Kevin Naiqama, Mark Percival, Regan Grace, Theo Fages, Alex Walmsley, Luke Thompson, Zeb Taia, Louie McCarthy-Scarsbrook, Morgan Knowles, Kyle Amor, Dom Peyroux, Matty Lees, Jack Ashworth, Aaron Smith, James Bentley, Lachlan Coote, Matty Costello.
Leeds’ 19-man squad: Jack Walker, Tom Briscoe, Kallum Watkins, Konrad Hurrell, Ash Handley, Richie Myler, Adam Cuthbertson, Matt Parcell, Brad Singleton, Trent Merrin, Brad Dwyer, Liam Sutcliffe, Brett Ferres, Mikolaj Oledzki, Cameron Smith, James Donaldson, Harry Newman, Wellington Albert, Ava Seumanufagai.