St Helens have rested nine players for their trip to London with an eye on next week’s Challenge Cup semi-final.
Coach Justin Holbrook caused some controversy earlier in the week when he revealed plans to give youth a chance against Super League’s bottom club.
It has caused complaints from fans of rival clubs to the Broncos, including Leeds and Hull KR, currently involved in a relegation scrap.
Even with a full strength side, St Helens suffered one of their two losses this season in the capital earlier in the season.
Out of their team go Lachlan Coote, Tommy Makinson, Kevin Naiqama, Jonny Lomax, Mark Percival, Theo Fages, Alex Walmsley, James Roby and Luke Thompson.
Four youngsters are included in the 19-man squad for the first time, with young hooker Josh Eaves, loose forward Callum Hazzard, centre Josh Simm and half-back Lewis Dodd getting the nod.
Jack Welsby returns for the first time since the game against London in June, while Joe Batchelor is included for the first time since April.
Danny Richardson, Adam Swift, Matty Costello, and Joseph Paulo also return.
London’s on-loan centre Ryan Morgan is not included against his parent club, with Olsi Krasniqi taking his place.
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St Helens 19-man squad: Grace, Richardson, Paulo, McCarthy-Scarsbrook, Knowles, Amor, Peyroux, Swift, Lees, Ashworth, Smith, Bentley, Costello, Batchelor, Eaves, Hazzard, Welsby, Simm, Dodd.
London 19-man squad: Abdull, Adebiyi, Battye, Butler, Cunningham, Davis, Dixon, Fleming, Fozard, Gee, Hellewell, Ioane, Kear, Krasniqi, Pitts, Richards, Walker, Williams, Yates