Stand-off Powell has suffered a calf injury, and is facing a potential absence of several weeks.
Prop Sutton is also out, having suffered his second concussion of the season last week.
Warriors skipper Sean O’Loughlin is also still out of action, along with centre Iain Thornley. Welsh prop Ben Flower is, of course, suspended.
Logan Tomkins, Dom Crosby and Dom Manfredi look set to be included in the Warriors squad to face Leeds this week.