Lomax sat out the win over Salford last weekend, and hasn’t recovered in time to line-up against the Warriors.
Saints have used 28 players already this season, including five debutants.
Wigan cruised to a 62-4 win over Widnes last weekend, and have no new injury concerns, with Sean O’Loughlin and Michael McIlorum both expected to shrug off knocks sustained on Saturday.
Wigan 19-man squad: Burke, Charnley, Crosby, Lloyd, Farrell, Flower, Goulding, Green, Hughes, McIlorum, O’Loughlin, Richards, Spencer, Smith, Taylor, Thornley, L Tomkins, S Tomkins, Tuson.
St Helens 19-man squad: Wellens, Gardner, Turner, Soliola, Meli, Perry, McCarthy-Scarsbrook, Wilkin, Manu, Laffranchi, Flanagan, Clough, Jones, Makinson, Ashe, Walmsley, Walker, Percival, Charnock.
Prediction: Wigan will be too strong for a St Helens side, missing some key players through injury – home win.
Last 10 meetings:
Wigan 18, St Helens 26 (SLR27, 7/9/12)
St Helens 16, Wigan 42 (SLR15, 27/5/12) (at Etihad Stadium, Manchester)
Wigan 18, St Helens 4 (CCQF, 12/5/12)
St Helens 10, Wigan 28 (SLR10, 6/4/12)
St Helens 26, Wigan 18 (SLQSF, 1/10/11)
Wigan 18, St Helens 26 (SLQPO, 18/9/11)
St Helens 12, Wigan 18 (CCSF, 6/8/11) (at Halliwell Jones Stadium, Warrington)
St Helens 10, Wigan 32 (SLR18, 17/6/11)
Wigan 28, St Helens 24 (SLR11, 22/4/11)
St Helens 16, Wigan 16 (SLR1, 12/2/11) (at Millennium Stadium, Cardiff)
Super League summary:
Wigan won 29 (includes win in 2010 Grand Final & wins in 2001, 2003 and 2004 play-offs)
St Helens won 27 (includes win in 2000 Grand Final & wins in 2000, 2002, 2009 and 2011 play-offs)
Wigan highest score: 65-12 (A, 1997) (also widest margin)
St Helens highest score: 57-16 (MM, 2008) (also widest margin)