Hull KR captain Joel Tomkins and Wigan forward Liam Farrell are set to miss the final round games.
Tomkins has been suspended for a match for Grade A punching in Hull KR’s loss to London last week.
He is set to miss Friday’s crunch clash against Salford.
Farrell has picked up a one-match ban for a Grade B dangerous throw in Wigan’s win over Catalans last Friday.
The back-rower will miss the Warriors’ match against Castleford on Thursday.
Elsewhere, Leigh prop Jake Emmitt has got a two-match ban for Grade B standing on.
Featherstone forward Jack Ormondroyd will serve a two-match suspension for Grade C foul and abusive language to a match official.
Halifax’s Brandon Moore has been charged with Grade D questioning the integrity of a match official – but his case has been referred to a tribunal.
In League 1, Hunslet centre Nathan Chappell has been charged with a Grade B dangerous throw and has been given a two-match ban.
Doncaster’s Brad Foster has been given a two-match penalty notice for Grade C dangerous throw.