St Helens will be without James Roby and Louie McCarthy-Scarsbrook on Friday, but Jake Connor could return for Hull FC.
Justin Holbrook has made two changes to his St Helens side that beat Catalans Dragons last week. James Bentley and Jack Welsby replace Roby and McCarthy-Scarsbrook.
Hull FC head coach Lee Radford has made just one change to his team that lost to Castleford Tigers last time out. England international Connor was originally ruled out for the season but he has recovered earlier than expected and could feature. He replaces Josh Griffin.
Saints 19-man squad: Jonny Lomax, Tommy Makinson, Mark Percival, Theo Fages, Kyle Amor, Zeb Taia, Jon Wilkin, Luke Douglas, Morgan Knowles, Luke Thompson, Danny Richardson, Regan Grace, Matty Lees, Jack Ashworth, Ben Barba, James Bentley, Aaron Smith, Matty Costello, Jack Welsby.
FC 19-man squad: Jamie Shaul, Bureta Faraimo, Carlos Tuimavave, Fetuli Talanoa, Scott Taylor, Danny Houghton, Dean Hadley, Jake Connor, Jordan Abdull, Danny Washbrook, Brad Fash, Sika Manu, Jez Litten, Jordan Lane, Hakim Miloudi, Masi Matongo, Cameron Scott, Liam Harris, Lewis Bienek.
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