Opposing head coach Craig Sandercock has taken the opposite approach, having rested a number of key players for the defeat to London last week.
In the backs, winger David Hodgson and centres Liam Salter and Graeme Horne replace Omari Caro, Chris Heil and Josh Guzdek, while in the pack hooker Josh Hodgson and prop Adam Walker are joined by second rowers Con Mika, Cory Paterson and Mickey Paea in the 19-man squad.
St Helens 19-man squad: Wellens, Turner, Soliola, Meli, Hohaia, Lomax, Roby, McCarthy-Scarsbrook, Puletua, Wilkin, Manu, Laffranchi, Clough, Jones, Makinson, Walmsley, Swift, Walker, Howarth.
Hull KR 19-man squad: Brown, Cox, Dobson, Griffin, Green, Hall, D. Hodgson, J. Hodgson, Horne, Lovegrove, Mika, Netherton, Paterson, Paea, Salter, Tuimavave, Walker, Welham, Withers.
Previous play-off meetings: None
Super League summary:
St Helens won 7
Hull KR won 7
St Helens highest score: 68-12 (H, 2010) (also widest margin)
Hull KR highest winning score: 28-24 (H, 2010) (Widest margin: 26-10, H, 2009)