Crucially, one of those is skipper Gareth Ellis, who has picked up a heel injury.
Stand-off Leon Pryce is also out of action with a shoulder problem.
Matty Bowen returns to the Wigan squad after missing out against Widnes. Larne Patrick makes way for him.
Hull FC (19-man squad): Abdull, Bowden, Fash, Green, Hadley, Houghton, Lineham, Logan, Michaels, Minichiello, Paea, Rankin, Shaul, Sneyd, Talanoa, Thompson, Watts, Westerman, Whiting.
Wigan (19-man squad): Hampshire, Charnley, Gelling, Bateman, Burgess; Williams, Smith, Crosby, McIlorum, Tautai, Tomkins, L. Farrell, O’Loughlin, Flower, Clubb, Mossop, Patrick.
Wigan have won their last five away meetings with Hull FC. The Black & Whites’ last home win against the Warriors was 18-10 on 13 February, 2009. Hull FC‘s Fetuli Talanoa has scored a try in all three of his previous games against Wigan.
Super League Summary:
Last 10 Meetings:
Wigan 13, Hull FC 12 (SLR5, 13/3/15)
Wigan 56, Hull FC 10 (SLR21, 18/7/14)
Hull FC 16, Wigan 44 (SLR12, 9/5/14)
Wigan 33, Hull FC 34 (SLR26, 30/8/13)
Hull FC 0, Wigan 16 (Challenge Cup Final, 24/8/13) (at Wembley Stadium)
Hull FC 20, Wigan 28 (SLR13, 26/4/13)
Wigan 48, Hull FC 10 (SLR23, 3/8/12)
Hull FC 12, Wigan 56 (SLR12, 22/4/12)
Hull FC 16, Wigan 30 (SLR23, 29/7/11)
Wigan 14, Hull FC 12 (SLR5, 13/3/11)