The London team will meet their Catalan counterparts at 3:00pm, followed two hours later by the clash between Grand Finalists Hull FC and newly promoted Hull Kingston Rovers.
Huddersfield Giants and Wakefield Trinity Wildcats (2:00pm) will open the following day, followed by Salford City Reds and Warrington Wolves (4:00pm), with the Bradford Bulls against Leeds Rhinos derby to finish off (6:00pm).
"We believe many supporters will make the Millennium Magic a full family weekend of sporting entertainment," said Rugby League's chief operating officer Nigel Wood.
"We would encourage everybody to secure their place now at what will be a hugely exciting event.
"The city of Cardiff has a tremendous track record of successfully hosting both rugby league and other major sports and we hope the experience for supporters to be just as vibrant for the Millennium Magic."