Rams coach Warren Jowitt will be without Rob Spicer (broken arm) for up to six weeks.
Spicer suffered the injury during Dewsbury’s 48-12 victory over Rochdale, a result that pleased Jowitt.
Jowitt said: “We were much better last week, especially in offence.
“We had a blip against Halifax but we put things right.
“We played very patiently and when we got our chances, we made sure we took them.”
Leigh prop Danny Meekin (knee) will face a late fitness test after suffering an injury in training on Tuesday.
Centurions assistant coach Paul Rowley said: “We were very good against Featherstone, it was like chalk and cheese compared to the week before. We forced a lot of errors and made a good team look very ordinary.
“We’ve trained well again this week and all the signs are positive. We’re looking forward to the challenge of backing up last week.”
He added: “It’s never easy at the best of times to go to Dewsbury, but at the moment our focus is on ourselves.
“If we can emulate and improve on last week’s performance then we should give ourselves a good shout.”