Championship winners Featherstone will travel to Jason Demetriou‘s Keighley in another interesting tie, while the only non-Championship team left in the competition, Barrow, will make the trip to Halifax.
The fourth quarter-final sees Sheffield host Hunslet.
One of the matches will be televised live by Premier Sports.
Leigh v Batley
Keighley v Featherstone
Halifax v Barrow
Sheffield v Hunslet