Warrington back-rower Ben Currie will go for scans on Monday after he limped off during the 54-6 Challenge Cup win over Bradford.
Coach Steve Price confirmed that the England international had hurt the same knee that was reconstructed in 2016 and that kept him out for virtually the whole of last season.
He had already crossed for two first half tries before being forced off around the half hour mark.
It was the only real negative on a comfortable afternoon for the Wolves, who registered their seventh successive win by running in 10 tries against their League One opponents.
Price said: “It’s too early to tell. He’ll go for scans on Monday and we’ll know more after that.
“I’m proud of the guys, it was a professional display.
“Those kind of games can be quite awkward, but to test the character and replicate the game plan and stay at it. It was a great opportunity for the young guys who haven’t had much game time.
“The club’s done quite well over the years (in the Challenge Cup) so the expectation is there to do well this year.
“Credit to Bradford, it’s quite difficult at times when you’re a few leagues below. Their fans were very passionate, and it would be great to have Bradford back on the map again with the history they’ve had over the previous years.”