Anthony Gelling will make his Leigh debut when they make their trip to Salford on Friday.
The 30-year-old centre has joined the Centurions for the season after recently playing rugby union in New Zealand.
A Cook Islands international, Gelling has made more than 150 career appearances for Wigan, New Zealand Warriors, Widnes and Warrington.
Leigh coach John Duffy said: “Gells is out of quarantine and is available this week so Anthony Gelling will play this week. He will give us a bit more strike on our edge.
“He looks fit. He has trimmed down a lot and he has been playing rugby union in New Zealand so he is in very good shape.”
Centre Iain Thornley is expected to return for Leigh on Friday after missing last week due to a bug. Prop Nathaniel Peteru suffered a knock to the head and he will be assessed more closely this week, Duffy confirmed.
Leigh have been dealt a blow though as star half-back Joe Mellor has suffered a hamstring tear and will be out for a few weeks.
Prop Adam Sidlow has sustained an MCL knee injury and will miss the next two to three weeks.
Former New Zealand and Samoa international Junior Sa’u is back in training but will only be available for selection from next week.