Hodgson has failed to recover from a hamstring injury, which saw the fullback leave the field prematurely for Warrington against Leeds.
Shannon McDonnell will directly replace Hodgson, while Sia Soliola moves from the second row to the centres to replace Sa.
David Fa’alogo, who was originally brought into the squad as 18th man, will start at loose forward. while Trent Waterhouse will occupy Soliola’s original second row spot.
Just who is the American football player who has been handed a trial by Catalans Dragons?
Oldham have been further strenghthened by threequarter Adam Clay inking a one-year deal at the club.
Widnes CEO James Rules has accepted the decision of an independent tribunal to fine his club £20,000 for the disorder at this year's Challenge Cup semi-final against Castleford.