Hodgson has failed to recover from a hamstring injury, which saw the fullback leave the field prematurely for Warrington against Leeds.
Shannon McDonnell will directly replace Hodgson, while Sia Soliola moves from the second row to the centres to replace Sa.
David Fa’alogo, who was originally brought into the squad as 18th man, will start at loose forward. while Trent Waterhouse will occupy Soliola’s original second row spot.
John Davidson sifts through the super spectacle of the Super League grand final, as Leeds complete a terrific treble and England announce its squad for the Kiwi series.
This epic clash will be the last time that Rhinos' rugged veterans Jamie Peacock, Kylie Leuluai and Kevin Sinfield will wear the Leeds colours, and they will be keen to end their playing careers on a high.
Hunslet have confirmed that Ayden Faal has signed a one-year deal to play for the club in 2016.