Hodgson has failed to recover from a hamstring injury, which saw the fullback leave the field prematurely for Warrington against Leeds.
Shannon McDonnell will directly replace Hodgson, while Sia Soliola moves from the second row to the centres to replace Sa.
David Fa’alogo, who was originally brought into the squad as 18th man, will start at loose forward. while Trent Waterhouse will occupy Soliola’s original second row spot.
Forty-20 editor-at-large Tony Hannan has concerns of his own about a British Medical Journal report…
Wigan Warriors have confirmed that Sam Tomkins will be re-joining the club for the 2016 season.