Nick Fozzard has resigned from his post as Commercial Manager at Castleford.
His wife Sarah has also resigned from her post as Marketing Manager.
Interim CEO Steve Gill said: "It is with disappointment that we confirm the departures of Sarah and Nick from the club. I’d like to take this opportunity to thank them both for their efforts.
"The Membership scheme has been a fantastic introduction to the club and Sarah played no small part in its delivery. We wish her well.
"Nick’s transition from player to commercial manager was amazing to see. We hope that his next venture in life is prosperous and one that gives him fulfilment.
"The aim of all remaining staff is to roll our sleeves up and ensure the backroom team are in a position to make the most of the positive start to the season made by the players and coaching staff."
The resignations follow on from last week's departure of chief executive Steve Ferres.
The Rugby Football Union say they will not stop Sale signing Castleford winger Denny Solomona.
RFL chief executive Nigel Wood as thrown his support behind England coach Wayne Bennett, saying the Australian has "challenged the sport in this country" to be better.
RFL boss Nigel Wood says the situation involving Castleford winger Denny Solomona is a concern for more than just rugby league.
Catalans Dragons have signed prop Paul Séguier and hooker Alrix Da Costa on full-time contracts.
Widnes captain Kevin Brown has signed a two-year deal with rivals Warrington.